Name
Yuki MORI
Degree
Ph.D
Affiliate

Assistant Professor

Researcher

Email
ymori [at] ifrec.osaka-u.ac.jp
Resources
Scientific Societies
International Society for Magnetic Resonance in Medicine
International Society of NeuroImmunology
Japanese Society for Magnetic Resonance in Medicine
The Japan Neuroscience Society
Japan Bioimaging Society

In-vivo cellular MR tracking
Monitoring of immune responses with in-vivo MRI scanner
Visualization of lymphatic morphology and function with MR Lymphography
Integrated technology for evaluation of neural plasticity and memory

Magnetic Resonance Imaging : MRI

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Neuroimmunology: Research about cross-talk between nervous system and immune system.

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Effects of Acupuncture or Oriental medicine

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Imaging of Qi: This is my Life-Work.

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My research focuses on the development novel non-invasive visualization techniques to unveil the cross-talk among neural and immune systems using by Magnetic Resonance Imaging (MRI) technologies.

For the past 60 years, the central nervous system has been considered immunologically privileged. Yet results from diverse fields show clear and convincing evidence of bidirectional communication between the nervous and immune systems. In addition to brain injury and neurological disease, there is now growing evidence that neural-immune crosstalk may even occur in non-disease conditions, including in the healthy brain. However, it is even more elusive how this cross-talk homeostatically maintained in the human and animal body.

To understand this cross-talk is important because it affects not only brain function but also psychiatric state, emotion, learning, and so on. Noninvasive techniques are desirable to identify real interactions between them.

We have been developing novel high-resolution, non-invasive and repeatable imaging techniques with ultra high-field 11.7-Tesla magnetic resonance scanners, allowing us to visualize biofunctional phenomena that could not be previously seen. In animal studies, we can visualize dynamical immune responses and immune cell migration at a single-cell level in situ.

I strongly believe that intravital MR imaging of cellular dynamics can sublimate our knowledge from cartoon to real biology. Fruits from our research have been incorporated in a better understanding of neuro-immunological systems, and we hope can easily translate to human studies near future.


Website of
Yuki Mori PhD, LicAc